Medical Weight Loss: Is Manjaro the Fastest Way to Lose Weight? Explained by a Cosmetic Dermatologist in Higashi Ward, Nagoya

 

Hello, I’m Koji Kato, a cosmetic dermatologist at W Skin Clinic Nagoya.

 

Today, I’ll explain whether Manjaro (tirzepatide) is the fastest way to lose weight in the field of medical weight loss.

 

■ 1. What Is Manjaro?

Manjaro is a dual incretin agonist that stimulates both the GLP-1 and GIP receptors.

 

Originally developed as a treatment for type 2 diabetes, it has gained attention for its remarkably powerful weight loss effects.

 

It was approved by the FDA in the U.S. in 2022 and later approved in Japan (as a diabetes medication), with global expansion for obesity treatment underway.

 

■ 2. Why Does Manjaro Help You Lose Weight So Quickly and Effectively?

① Synergistic Action of GIP + GLP-1

Traditional GLP-1 receptor agonists (such as semaglutide/“Rybelsus” or liraglutide/“Victoza”) primarily delay gastric emptying and suppress appetite.

 

Manjaro, on the other hand, stimulates GIP (glucose-dependent insulinotropic polypeptide) as well, which further enhances:

 

Prolonged satiety

 

Optimized insulin secretion and increased fat metabolism

 

Suppression of post-meal blood sugar spikes

 

As a result, it creates a physiological environment in which you feel full on less food while boosting your metabolism—an ideal combination for weight loss.

 

■ 3. Clinical Results (SURMOUNT Study)

In the SURMOUNT-1 study (NEJM, 2022):

 

Patients receiving Manjaro 15mg over 72 weeks lost an average of 22.5% of their body weight.

 

By comparison, semaglutide (e.g., Rybelsus) over the same period showed an average reduction of about 14–15%.

 

➡ These results show that Manjaro leads to faster and greater weight loss than existing GLP-1 drugs.

 

■ 4. Who Is Manjaro Best For?

✔ Those who want to lose weight quickly (within 3–6 months)

✔ Those who struggle with appetite control

✔ People with high levels of visceral fat, prediabetes, or metabolic syndrome

✔ Individuals with other lifestyle-related conditions like dyslipidemia or hypertension

✔ Patients who did not respond well to previous GLP-1 medications

 

■ 5. Precautions and Side Effects

Most common side effects: nausea, bloating, and constipation, especially in the early stages

 

Because of rapid weight loss, there is also a risk of muscle mass loss—adequate protein intake and exercise are essential

 

For patients with severe obesity, medical supervision and follow-up are strongly recommended

 

■ Conclusion: Manjaro Is a Leading Option for Rapid Weight Loss

✅ Among all medical weight loss treatments available today, Manjaro is considered one of the most powerful and fastest-acting injectable options.

✅ It is especially suitable for those who want quick results or have not responded well to conventional GLP-1 drugs.

✅ If your goal is to lose weight as quickly as possible, Manjaro may be your best choice.

 

💡 To prevent rebound and maintain results, combining Manjaro with body contouring devices like Vanquish or EMSLIM can be highly effective.

We can provide personalized combination treatment plans depending on your body composition and goals—please feel free to reach out for consultation.